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Medical Informatics

Medical Informatics (MI) at Linköping University was founded in 1973. Head of the group is Professor Hans Knutsson.

The overall purpose of systems developed in the field of medical informatics is to extract and present clinically relevant information. Medical information appears in many different forms: Text, Parameters,Value Measurements, Time Courses, Images, Volumes, Image and Volume Sequences. Methods to attain new types of information is continuously being developed and the detail and quality of recorded data is increasing rapidly. Huge amounts of potentially relevant information can be tied to one single patient. In addition it is necessary to be able to integrate and analyze information from a large number of patients and time instances. This development has led to a situation where we are at risk of drowning in the overwhelming flow of information.

To be able to extract the relations that are pertinent in a given situation and to present them in a way that is simple to understand is rapidly becoming the main problem. Efficient solutions of this problem will be crucial components in future health care. To develop principles and methods for such solutions is the goal the research in the field of medical informatics.

To meet these challenges research is in general directed towards the development of adaptive and machine learning techniques for representation, presentation and visualization of multimodal, multivariate and multidimensional medical data and knowledge. In particular the research group focuses on the development of systems for medical decision support and medical image analysis. A number of graduate and undergraduate courses focusing on these topics are regularly given by the Medical Informatics group.

MI is a part of the Department of Biomedical Engineering, and a part of the Linköping Institute of Technology. MI is also affiliated to the Center for Medical Image Science and Visualisation, CMIV, and the Faculty of Health Sciences. Presently the group consists of 20 people.


Medical Image Analysis

Health Informatics


Recent publications:

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2017
Per Sidén, Anders Eklund, David Bolin, Mattias Villani, "Fast Bayesian whole-brain fMRI analysis with spatial 3D priors", NeuroImage, 146: 211-225, 2017.
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2016
Anezka Hucikova, Ankica Babic, "Overcoming Constraints in Healthcare with Cloud Technology", UNIFYING THE APPLICATIONS AND FOUNDATIONS OF BIOMEDICAL AND HEALTH INFORMATICS, Studies in Health Technology and Informatics, 165-168, 2016.
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Anezka Hucikova, Ankica Babic, "Cloud Computing in Healthcare: A Space of Opportunities and Challenges", TRANSFORMING HEALTHCARE WITH THE INTERNET OF THINGS, Studies in Health Technology and Informatics, 122-122, 2016.
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Greger Knudsen, Ankica Babic, "Identifying Dyscalculia Symptoms Related to Magnocellular Reasoning Using Smartphones", UNIFYING THE APPLICATIONS AND FOUNDATIONS OF BIOMEDICAL AND HEALTH INFORMATICS, Studies in Health Technology and Informatics, 229-232, 2016.
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Olof Dahlqvist Leinhard, Jennifer Linge, Janne West, Jimmy Bell, Magnus Borga, "Body Composition Profiling using MRI - Normative Data for Subjects with Diabetes Extracted from the UK Biobank Imaging Cohort", Radiological Society of North America 2016, the 102nd Scientific Assembly and Annual Meeting, Chicago, Illinois, USA, November 27 - December 2, 2016, 2016.
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Olof Dahlqvist Leinhard, Jennifer Linge, Janne West, Jimmy Bell, Magnus Borga, "Body Composition Profiling using MRI - Normative Data for Subjects with Cardiovascular Disease Extracted from the UK Biobank Imaging Cohort", Radiological Society of North America 2016, the 102nd Scientific Assembly and Annual Meeting, Chicago, Illinois, Usa, November 27 - December 2, 2016, 2016.
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Anette Karlsson, Jennifer Linge, Janne West, Jimmy Bell, Magnus Borga, Olof Dahlqvist Leinhard, "Defining Sarcopenia with MRI - Establishing Threshold Values within a Large-Scale Population Study", Radiological Society of North America 2016, 102nd Scientific Assembly and Annual Meeting, Chicago, Illinois, USA, November 27 - December 2, 2016, 2016.
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Anette Karlsson, Olof Dahlqvist Leinhard, Ulrika Åslund, Janne West, Thobias Romu, Örjan Smedby, Peter Zsigmond, Anneli Peolsson, "An Investigation of Fat Infiltration of the Multifidus Muscle in Patients With Severe Neck Symptoms Associated With Chronic Whiplash-Associated Disorder", Journal of Orthopaedic and Sports Physical Therapy, 46(10): 886-893, 2016.
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Daniel Karlsson, Andrius Budrionis, Ann Bygholm, Mariann Fossum, Conceição Granja, Gunnar Hartvigsen, Ole Hejlesen, Maria Hägglund, Monika Alise Johansen, Santiago Martinez, Carl E. Moe, Luis Marco-Ruiz, Vivian Vimarlund, Kassaye Y. Yigzaw, "Proceedings from The 14th Scandinavian Conference on Health Informatics 2016: Gothenburg, Sweden, April 6-7 2016", Linköping Electronic Conference Proceedings, No. 122, 2016.
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Janne West, Olof Dahlqvist Leinhard, Thobias Romu, Rory Collins, Steve Garratt, Jimmy Bell, Magnus Borga, E. Louise Thomas, "Feasibility of MR-based Body Composition Analysis in Large Scale Population Studies", PLoS ONE, 11(9), 2016.
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Thobias Romu, Nils Dahlström, Olof Dahlqvist Leinhard, Magnus Borga, "Robust Water Fat Separated Dual-Echo MRI by Phase-Sensitive Reconstruction", Magnetic Resonance in Medicine, (Accepted), 2016.
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Meenu Rohini Rajan, Elin Nyman, Preben Kjölhede, Gunnar Cedersund, Peter Strålfors, "Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes", Journal of Biological Chemistry, 291(30): 15806-15819, 2016.
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Mayank Goswami, Snehlata Shakya, Anupam Saxena, Prabhat Munshi, "Optimal Spatial Filtering Schemes and Compact Tomography Setups", Research in nondestructive evaluation (Print), 27(2): 69-85, 2016.
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Carl-Fredrik Westin, Hans Knutsson, Ofer Pasternak, Filip Szczepankiewicz, Evren Özarslan, Danielle van Westen, Cecilia Mattisson, Mats Bogren, Lauren J O'Donnell, Marek Kubicki, Daniel Topgaard, Markus Nilsson, "Q-space trajectory imaging for multidimensional diffusion MRI of the human brain", NeuroImage, 135: 345-362, 2016.
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Anders Eklund, Thomas Nichols, Hans Knutsson, "Cluster failure: Why fMRI inferences for spatial extent have inflated false-positive rates", Proceedings of the National Academy of Sciences of the United States of America, 113(28): 7900-7905, 2016.
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William Haufe, Jonathan Hooker, Alexandra Schlein, Nikolaus Szeverenyi, Magnus Borga, Olof Dahlqvist Leinhard, Thobias Romu, Patrik Tunón, Santiago Horgan, Garth Jacobsen, Jeffrey B Schwimmer, Scott B Reeder, Claude B. Sirlin, "Feasibility of an automated tissue segmentation technique in a longitudinal weight loss study", International Society for Magnetic Resonance in Medicine Annual Meeting & Exhibition, Singapore, May 7-13, 2016, 2016.
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Thobias Romu, Janne West, Anna-Clara Spetz, Hanna Lindblom, Lotta Lindh Åstrand, Mats Hammar, Magnus Borga, Olof Dahlqvist Leinhard, "The effect of flip-angle on body composition using calibrated water-fat MRI.", International Society for Magnetic Resonance in Medicine Annual Meeting & Exhibition, Singapore, May 7-13, 2016, 2016.
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Michael Middleton, William Haufe, Jonathan Hooker, Magnus Borga, Olof Dahlqvist Leinhard, Thobias Romu, Patrik Tunón, Nick Szeverenyi, Gavin Hamilton, Tanya Wolfson, Anthony Gamst, Rohit Loomba, Claude B. Sirlin, "Repeatability and accuracy of a novel, MRI-based, semi-automated analysis method for quantifying abdominal adipose tissue and thigh muscle volumes", International Society for Magnetic Resonance in Medicine Annual Meeting & Exhibition, Singapore, May 7-13, 2016, 2016.
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Janne West, Olof Dahlqvist Leinhard, Thobias Romu, E. Louise Thomas, Magnus Borga, Jimmy Bell, "Body Composition Analysis In Large Scale Population Studies using Dixon Water-Fat Separated Imaging", International Society for Magnetic Resonance in Medicine Annual Meeting & Exhibition, Singapore, May 7-13, 2016, 2016.
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David Newman, Christian Kelly-Morland, Olof Dahlqvist Leinhard, Bahman Kasmai, Richard Greenwood, Paul Malcolm, Thobias Romu, Magnus Borga, Andoni Toms, "Test–retest reliability of rapid whole body and compartmental fat volume quantification on a widebore 3T MR system in normal-weight, overweight, and obese subjects", Journal of Magnetic Resonance Imaging, (Epub ahead of print), 2016.
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Thobias Romu, Vavruch Camilla, Olof Dahlqvist Leinhard, Joakim Tallberg, Nils Dahlström, Anders Persson, Mikael Heglind, Martin Lidell, Sven Enerbäck, Magnus Borga, Fredrik Nyström, "A randomized trial of cold-exposure on energy expenditure and supraclavicular brown adipose tissue volume in humans", Metabolism, 65(6): 926-934, 2016.
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Elin Nyman, Yvonne J W Rozendaal, Gabriel Helmlinger, Bengt Hamrén, Maria C Kjellsson, Peter Strålfors, Natal A W van Riel, Peter Gennemark, Gunnar Cedersund, "Requirements for multi-level systems pharmacology models to reach end-usage: the case of type 2 diabetes", Interface Focus, 6(2): 1-14, 2016.
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Mikael Nyström, Håkan Örman, Leili Lind, Erik Sundvall, Nosrat Shahsavar, Daniel Karlsson, "Det krävs en riktad satsning på e-hälsa", Dagens medicin, 22-, 2016.
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Tom Oluoch, Abraham Katana, Daniel Kwaro, Xenophon Santas, Patrick Langat, Samuel Mwalili, Kimeu Muthusi, Nicky Okeyo, James K. Ojwang, Ronald Cornet, Ameen Abu-Hanna, Nicolette de Keizer, "Effect of a clinical decision support system on early action on immunological treatment failure in patients with HIV in Kenya: a cluster randomised controlled trial", LANCET HIV, 3(2): E76-E84, 2016.
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The publication list is extracted from the DiVA - Academic Archive Online - publishing system. The extraction software is developed by Johan Wiklund.

Sidansvarig: Hans Knutsson
Senast uppdaterad: 2014-12-12