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Medical Informatics

Medical Informatics (MI) at Linköping University was founded in 1973. Head of the group is Professor Hans Knutsson.

The overall purpose of systems developed in the field of medical informatics is to extract and present clinically relevant information. Medical information appears in many different forms: Text, Parameters,Value Measurements, Time Courses, Images, Volumes, Image and Volume Sequences. Methods to attain new types of information is continuously being developed and the detail and quality of recorded data is increasing rapidly. Huge amounts of potentially relevant information can be tied to one single patient. In addition it is necessary to be able to integrate and analyze information from a large number of patients and time instances. This development has led to a situation where we are at risk of drowning in the overwhelming flow of information.

To be able to extract the relations that are pertinent in a given situation and to present them in a way that is simple to understand is rapidly becoming the main problem. Efficient solutions of this problem will be crucial components in future health care. To develop principles and methods for such solutions is the goal the research in the field of medical informatics.

To meet these challenges research is in general directed towards the development of adaptive and machine learning techniques for representation, presentation and visualization of multimodal, multivariate and multidimensional medical data and knowledge. In particular the research group focuses on the development of systems for medical decision support and medical image analysis. A number of graduate and undergraduate courses focusing on these topics are regularly given by the Medical Informatics group.

MI is a part of the Department of Biomedical Engineering, and a part of the Linköping Institute of Technology. MI is also affiliated to the Center for Medical Image Science and Visualisation, CMIV, and the Faculty of Health Sciences. Presently the group consists of 20 people.


Medical Image Analysis

Health Informatics


Recent publications:

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2016
Thobias Romu, Vavruch Camilla, Olof Dahlqvist Leinhard, Joakim Tallberg, Nils Dahlström, Anders Persson, Mikael Heglind, Martin Lidell, Sven Enerbäck, Magnus Borga, Fredrik Nyström, "A randomized trial of cold-exposure on energy expenditure and supraclavicular brown adipose tissue volume in humans", Metabolism, 65(6): 926-934, 2016.
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Elin Nyman, Yvonne J W Rozendaal, Gabriel Helmlinger, Bengt Hamrén, Maria C Kjellsson, Peter Strålfors, Natal A W van Riel, Peter Gennemark, Gunnar Cedersund, "Requirements for multi-level systems pharmacology models to reach end-usage: the case of type 2 diabetes.", Interface Focus, 6(2): 1-14, 2016.
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Mikael Nyström, Håkan Örman, Leili Lind, Erik Sundvall, Nosrat Shahsavar, Daniel Karlsson, "Det krävs en riktad satsning på e-hälsa", Dagens medicin, 22-, 2016.
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Tom Oluoch, Abraham Katana, Daniel Kwaro, Xenophon Santas, Patrick Langat, Samuel Mwalili, Kimeu Muthusi, Nicky Okeyo, James K. Ojwang, Ronald Cornet, Ameen Abu-Hanna, Nicolette de Keizer, "Effect of a clinical decision support system on early action on immunological treatment failure in patients with HIV in Kenya: a cluster randomised controlled trial", LANCET HIV, 3(2): E76-E84, 2016.
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Rama Chellappa, Anders Heyden, Denis Laurendeau, Michael Felsberg, Magnus Borga, "Special issue on ICPR 2014 awarded papers", Elsevier, No. Vol. 72, 2016.
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Sergio Miranda Freire, Douglas Teodoro, Fang Wei-Kleiner, Erik Sundvall, Daniel Karlsson, Patrick Lambrix, "Comparing the Performance of NoSQL Approaches for Managing Archetype-Based Electronic Health Record Data", PLoS ONE, 11(3), 2016.
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Erik Joukes, Ronald Cornet, Martine C. de Bruijne, Nicolette F. de Keizer, "Eliciting end-user expectations to guide the implementation process of a new electronic health record: A case study using concept mapping", International Journal of Medical Informatics, 87: 111-117, 2016.
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Pernilla Peterson, Thobias Romu, Hakan Brorson, Olof Dahlqvist Leinhard, Sven Mansson, "Fat Quantification in Skeletal Muscle Using Multigradient-Echo Imaging: Comparison of Fat and Water References", Journal of Magnetic Resonance Imaging, 43(1): 203-212, 2016.
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2015
Hans Knutsson, Magnus Herberthson, Carl-Fredrik Westin, "An Iterated Complex Matrix Approach for Simulation and Analysis of Diffusion MRI Processes", MEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION - MICCAI 2015, PT I, Lecture Notes in Computer Science, Vol. 9349, 61-68, 2015.
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Kathrin Dentler, Ronald Cornet, "Intra-axiom redundancies in SNOMED CT", Artificial Intelligence in Medicine, 65(1): 29-34, 2015.
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Olivier Cros, "Image Analysis and Visualization of the Human Mastoid Air Cell System", Linköping Studies in Science and Technology. Thesis, No. 1730, 2015.
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Olivier Cros, Michael Gaihede, Mats Andersson, Hans Knutsson, "Structual Analysis of Micro-channels in Human Temporal Bone", IEEE 12th International Symposium on Biomedical Imaging (ISBI), 2015 IEEE 12th International Symposium on, 9-12, 2015.
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Johanna Skarpman Munter, Jens Sjölund, "Dose-volume histogram prediction using density estimation", Physics in Medicine and Biology, 60(17): 6923-6936, 2015.
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Magnus Borga, E. Louise Thomas, Thobias Romu, Johannes Rosander, Julie Fitzpatrick, Olof Dahlqvist Leinhard, Jimmy D Bell, "Validation of a Fast Method for Quantification of Intra-abdominal and Subcutaneous Adipose Tissue for Large Scale Human Studies", NMR in Biomedicine, 28(12): 1747-1753, 2015.
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Tom Oluoch, Nicolette de Keizer, Patrick Langat, Irene Alaska, Kenneth Ochieng, Nicky Okeyo, Daniel Kwaro, Ronald Cornet, "A structured approach to recording AIDS-defining illnesses in Kenya: A SNOMED CT based solution", Journal of Biomedical Informatics, 56: 387-394, 2015.
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Catalina Martinez-Costa, Ronald Cornet, Daniel Karlsson, Stefan Schulz, Dipak Kalra, "Semantic enrichment of clinical models towards semantic interoperability. The heart failure summary use case", JAMIA Journal of the American Medical Informatics Association, 22(3): 565-576, 2015.
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Klara Renström, "Automatic age estimation of children based on brain matter composition using quantitative MRI", Student thesis, LiTH-IMT/MI30-A-EX--15/528--SE, 2015.
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Anders Eklund, Thomas Nichols, Mats Andersson, Hans Knutsson, "Empirically Investigating the Statistical Validity of SPM, FSL and AFNI for Single Subject fMRI Analysis", International Symposium on Biomedical Imaging (ISBI), 2015.
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Kirstine Rosenbeck Goeg, Ronald Cornet, Stig Kjaer Andersen, "Clustering clinical models from local electronic health records based on semantic similarity", Journal of Biomedical Informatics, 54: 294-304, 2015.
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Rodrigo Moreno, Magnus Borga, Eva Klintström, Torkel Brismar, Örjan Smedby, "Anisotropy Estimation of Trabecular Bone in Gray-Scale: Comparison Between Cone Beam and Micro Computed Tomography Data", Developments in Medical Image Processing and Computational Vision, Lecture Notes in Computational Vision and Biomechanics, No. 19, 207-220, 2015.
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Arash Gharehbaghi, Magnus Borga, Birgitta Janerot Sjöberg, Ask Per, "A novel method for discrimination between innocent and pathological heart murmurs", Medical Engineering and Physics, 37(7): 674-682, 2015.
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Stefanie Eriksson, Samo Lasic, Markus Nilsson, Carl-Fredrik Westin, Daniel Topgaard, "NMR diffusion-encoding with axial symmetry and variable anisotropy: Distinguishing between prolate and oblate microscopic diffusion tensors with unknown orientation distribution", Journal of Chemical Physics, 142(10): 104201-, 2015.
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Gustaf Johansson, "A Global Linear Optimization Framework for Adaptive Filtering and Image Registration", Linköping Studies in Science and Technology. Thesis, No. 1711, 2015.
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Thobias Romu, Louise Elander, Olof Dahlqvist Leinhard, Martin Lidell, Matthias Betz, Anders Persson, Sven Enerbäck, Magnus Borga, "Characterization of Brown Adipose Tissue by water-fat separated Magnetic Resonance Imaging", Journal of Magnetic Resonance Imaging, 42(6): 1639-1645, 2015.
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Daniel Andersson, "Automatic vertebrae detection and labeling in sagittal magnetic resonance images", Student thesis, LiTH-IMT/MI30-A-EX--15/525--SE, 2015.
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The publication list is extracted from the DiVA - Academic Archive Online - publishing system. The extraction software is developed by Johan Wiklund.

Sidansvarig: Hans Knutsson
Senast uppdaterad: 2014-12-12