Biomedical modelling and simulation
The research at the division of biomedical modelling and simulation includes the vast area from traditional basic physiology to advanced clinical applications. Presently, one focus is the biofluid mechanics of the heart and the greater vessels, another the mechanics of the myocardium. In biomedical modelling and simulation we are using tools from mathematics, mechanics and phyics in order to analyse structure and function of complex biological systems. The advanced model development is based on high quality measurements. Currently, non-invasive measurement techniques are utilized combined with computer models for data assimilation. The rapid development in computers enables the development of inividually based models for advanced diagnosis, intervention planning and follow-up. The research area is cross-disciplinary and presently we are participating in the development of Center for Medical Image Science and Visualization (CMIV), a joint effort between the University and the University Hopital. The division has a long standing research collaboration with the Department of Mechanical Engineering (IKP) and National Supercomputer Centre (NSC) at Linköpings universitet.
Contact person: Prof Matts Karlsson
(A) A sketch of the heart with some markers implanted in the left ventricular wall and three four-bead-columns inserted transmurally in a lateral region of the myocardium. The bead array in magnification. (B) Values during one heart beat (end-diastole, ED, to ED) for one animal (sheep). Left axis: The radial component of the strain tensor computed at three transmural depths (in % of wall thickness from epicardium) at the position of the bead array. Right axis: The left ventricular pressure, LVP, [mmHg].
Sidansvarig: Matts Karlsson
Senast uppdaterad: 2012-03-31